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phenotype 568 words KG: inflammation
Contents

INFLAMMATION

🔬 Protein Info
Gene Symbolinflammation
Associated Diseasesaging, Alzheimer Disease, Alzheimer'S Disease, Alzheimer's disease and related dementias, Asthma, atherosclerosis
Known Drugs/CompoundsACBA, Artemisia annua, CCR2 blockade, Luteolin, Quercetin, sesquiterpenoids
InteractionsAMPK
KG Connections1152 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (39)

Microglial AIM2 Inflammasome as the Primary Driver of TDP-43
Score: 0.82Beta-Hydroxybutyrate Receptor (HCAR2) Signaling Links Ketone
Score: 0.81SIRT1/PGC-1α Axis Activation to Preserve Mitochondrial Resil
Score: 0.78GRN/progranulin lysosomal insufficiency across FTD, ALS-spec
Score: 0.76Microglia-Mediated Neuroinflammation as a Disease-Amplifying
Score: 0.72Microglial Disease-Associated States: TREM2-Independent Path
Score: 0.71TLR4/MyD88/NF-κB Axis Blockade to Interrupt LPS-Mediated Gut
Score: 0.70AQP4 Dysregulation Promotes Neuroinflammation Through Impair
Score: 0.68Microglial TREM2 state determines whether C1q-tagged substra
Score: 0.67GFAP-Bearing Circulating Extracellular Vesicles Originating
Score: 0.67NeuroD1-Mediated Astrocyte Reprogramming Attenuates Neuroinf
Score: 0.65APOE4 preferentially signals through LRP1 over LDLR, alterin
Score: 0.61STING Antagonism Prevents Acute-to-Chronic Neuroinflammation
Score: 0.60Cardiovascular-Neuroinflammation Crosstalk Interruption
Score: 0.59Astrocyte cGAS/STING Activation Converts Protective into Des
Score: 0.58Neuroinflammation-Driven TDP-43 Mislocalization via Microgli
Score: 0.58Astrocyte-targeted LNP-APOE4 silencing to restore lipid home
Score: 0.57PINK1/PARK2-Mediated Mitophagy Enhancement for Neuroinflamma
Score: 0.57BET Bromodomain Inhibition for Neuroinflammation Suppression
Score: 0.55Lactate/Pyruvate Ratio Dynamics in CSF as a Neuroinflammatio
Score: 0.53
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Knowledge Graph (12 edges)

AMPK inhibits inflammation
inflammation associated_with aging
NLRP3 associated_with inflammation
Quercetin inhibits inflammation
inflammation regulates PIEZO1
inflammation regulates PIEZO2
autophagy_pathway inhibits inflammation
oxidative_stress activates inflammation
inflammation activates fibrosis
NASH associated_with inflammation

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