gene 700 words KG: NLRP1
Contents

NLRP1 Gene

🧬 Gene Info
Gene SymbolNLRP1
Full NameNLRP1 (NLR Family Pyrin Domain Containing 1)
Chromosome17p13.2
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues with highest expression in:
Molecular Weight213 kDa
Amino Acids1839 aa
PathwaysInflammasome, Pyroptosis
UniProt IDQ9Y258
NCBI Gene ID22821
Ensembl IDENSG00000091592
GeneCardsNLRP1
Human Protein AtlasNLRP1
Associated DiseasesAls, Autoimmune, Cancer, Carcinoma, Cardiovascular
Known Drugs/Compoundsrapamycin
InteractionsAGING, AIFM1, AIM2, Akt, AKT, ALZHEIMER
KG Connections355 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

NLRP1 associated_with DEPRESSION
NLRP1 activates BAX
BAX activates NLRP1
NLRP1 associated_with Major depressive disorder
NLRP1 regulates autophagy
NLRP1 activates pro-inflammatory cytokines
NLRP1 associated_with major depressive disorder
chronic social defeat stress activates NLRP1
NLRP1 expressed_in P62
NLRP1 activates SQSTM1

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