concept

MTORC2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MTORC2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

25Connections

0Hypotheses

0Analyses

14Outgoing

11Incoming

0Experiments

0Debates

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💡 Concept Info

Name	MTORC2
Key Genes/Proteins	AKT, FLRT2, GPCR, GROWTH_FACTOR_RECEPTORS, MTOR
Related Diseases	MITOXYPERIOSIS

Pathway Diagram

graph TD
    MTORC2["MTORC2"]
    MTORC2 -->|"regulates"| Cell_Death["Cell Death"]
    MTORC2 -->|"regulates"| Mitoxyperilysis["Mitoxyperilysis"]
    MTORC2 -->|"activates"| AKT["AKT"]
    MTORC2 -->|"phosphorylates"| PKC["PKC"]
    MTORC2 -->|"phosphorylates"| SGK["SGK"]
    MTORC2 -->|"mediates"| Cell_Growth["Cell Growth"]
    MTORC2 -->|"mediates"| Cell_Proliferation["Cell Proliferation"]
    MTOR["MTOR"] -->|"component_of"| MTORC2
    GROWTH_FACTOR_RECEPTORS["GROWTH FACTOR RECEPTORS"] -->|"activates"| MTORC2
    G_PROTEIN_COUPLED_RECEPTORS["G-PROTEIN COUPLED RECEPTORS"] -->|"activates"| MTORC2
    Anabolic_Signals["Anabolic Signals"] -->|"activates"| MTORC2
    RPL26["RPL26"] -->|"activates"| MTORC2
    Nutrient_Limitation["Nutrient Limitation"] -->|"modulates"| MTORC2
    GPCR["GPCR"] -->|"activates"| MTORC2

Outgoing (14)

Target	Relation	Type	Str
Mitoxyperilysis	regulates	process	0.95
Cell Death	regulates	process	0.95
PKC	phosphorylates	protein	0.90
SGK	phosphorylates	protein	0.90
Cell Growth	mediates	process	0.90
AKT	phosphorylates	protein	0.90
Cell Survival	mediates	process	0.90
Cell Proliferation	mediates	process	0.90
AKT	activates	protein	0.90
AKT	activates	protein	0.87
Metabolic Reprogramming	mediates	process	0.80
MITOXYPERIOSIS	regulates	phenotype	0.72
PKC	activates	protein	0.72
SGK	activates	protein	0.72

Incoming (11)

Source	Relation	Type	Str
MTOR	component_of	gene	0.95
MTOR	part_of	gene	0.90
G-PROTEIN COUPLED RECEPTORS	activates	receptor	0.85
Anabolic Signals	activates	process	0.85
GROWTH FACTOR RECEPTORS	activates	receptor	0.85
FLRT2	regulates	gene	0.80
RPL26	activates	protein	0.80
Nutrient Limitation	modulates	process	0.75
PTEN	inhibits	gene	0.70
GPCR	activates	protein	0.64
GROWTH_FACTOR_RECEPTORS	activates	protein	0.64

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MTORC2 in their description or question text

No additional research found