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mechanism 1,525 words KG: MAPT
Contents

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⚙ Mechanism Info
NameMAPT
Key Genes/Proteins0N3R, A2M, ABCA1, ABCA2, ABCA7, ACE
Related Diseases4R Tauopathy
Linked Hypotheses5 hypotheses

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🌐 Cross-references

Wikipedia

Related Hypotheses (3)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.76Autophagosome Maturation Checkpoint Control
Score: 0.71VCP-Mediated Autophagy Enhancement
Score: 0.59

Related Analyses (30)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedSleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archivedSleep disruption as cause and consequence of neurodegenerati
neurodegeneration · completedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived

Related Experiments (3)

Tau depletion effects on neuronal development in primary cul
exploratory · proposed · Score: 0.90Microtubule domain analysis in adult axons
exploratory · proposed · Score: 0.80Pre-Symptomatic Tau Detection in MAPT Mutation Carriers
clinical · proposed · Score: 0.40

Knowledge Graph (12 edges)

MAPT encodes TAU
NCSTN interacts_with MAPT
FAS interacts_with MAPT
TNF interacts_with MAPT
LMNA interacts_with MAPT
APH1B interacts_with MAPT
APOE activates MAPT
IL6 interacts_with MAPT
SREBF1 activates MAPT
PSEN2 activates MAPT

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