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mechanism 1,042 words KG: MAPT
Contents

ftdp-17-genetics-mapt-mutations

⚙ Mechanism Info
NameMAPT
Key Genes/Proteins0N3R, A2M, ABCA1, ABCA2, ABCA7, ACE
Related Diseases4R Tauopathy
Linked Hypotheses5 hypotheses

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (2)

Multi-Modal CRISPR Platform for Simultaneous Editing and Mon
Score: 0.63Synthetic Biology Rewiring via Orthogonal Receptors
Score: 0.65

Related Analyses (30)

Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · completedSleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archivedSEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived

Related Experiments (13)

TDP-43 PET Ligand Development for FTD and ALS
clinical · proposed · Score: 0.40Progranulin Replacement Therapy for FTD — Vector Development
clinical · proposed · Score: 0.40Mechanism: Progranulin Loss and TDP-43 Pathology in FTD
validation · proposed · Score: 0.40Proposed experiment from debate on TDP-43 undergoes liquid-l
falsification · proposed · Score: 0.40Autophagy Enhancement Drug Screening for Neurodegeneration
clinical · proposed · Score: 0.40

Knowledge Graph (12 edges)

MAPT encodes TAU
NCSTN interacts_with MAPT
FAS interacts_with MAPT
TNF interacts_with MAPT
LMNA interacts_with MAPT
APH1B interacts_with MAPT
APOE activates MAPT
IL6 interacts_with MAPT
SREBF1 activates MAPT
PSEN2 activates MAPT

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