Contents

VEGF and Angiogenesis Dysregulation in CBS/PSP

🔬 Protein Info

Gene Symbol	ent-gene-c42d399b
VEGF-B	Regulates vascular maintenance and endothelial cell survival through VEGFR-1 signaling
VEGF-C/D	Primarily regulate lymphatic angiogenesis via VEGFR-3
Basal ganglia	40-60% reduction in VEGF-A immunoreactivity
Subthalamic nucleus	Severe VEGF depletion correlating with neuronal loss
Brainstem	Marked reduction in midbrain and pons
Motor cortex	Moderate decrease in cortical layers[@vegf2023]
KG Connections	2 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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