gene 1,058 words KG: LIF
Contents

LIF — Leukemia Inhibitory Factor

🧬 Gene Info
Gene SymbolLIF
Full NameLeukemia Inhibitory Factor
AliasesPage for LIF Receptor Protein
Chromosome5p13.1
FunctionThe LIF gene encodes a 202-amino acid secreted glycoprotein that acts as a multifunctional cytokine:
Molecular Weight190 kDa
Amino Acids202 aa
Exons20
PathwaysMAPK, PI3K
UniProt IDP15018
NCBI Gene ID3977
Ensembl IDENSG00000128342
OMIM159446
GeneCardsLIF
Human Protein AtlasLIF
Associated Diseasesmultiple sclerosis
InteractionsActin, AND, App, ASTROCYTE, ASTROCYTES, BDNF
KG Connections125 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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Knowledge Graph (12 edges)

LIF activates EGFR
LIF protects_against neurite damage
EGFR activates LIF
STAT3 activates LIF
LIFR expressed_in LIF
GFAP expressed_in LIF
LIF expressed_in LIFR
LIF activates STAT3
SOX2 activates LIF
LIFR activates LIF

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