Contents

LRRK2 Inhibitor Therapy

🔬 Protein Info

Gene Symbol	ent-gene-9f063e98
Primary Target	LRRK2 kinase domain (ATP-binding site)
Modality	Small-molecule kinase inhibitor (ATP-competitive)
Indication	Parkinson's disease (LRRK2-associated and sporadic)
Patient Selection	LRRK2 mutation carriers (G2019S, R1441C/G, I2020T) and sporadic PD with elevated LRRK2 activity
KG Connections	2 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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