concept

GSPT1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GSPT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections

0Hypotheses

0Analyses

18Outgoing

6Incoming

0Experiments

0Debates

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💡 Concept Info

Name	GSPT1
Key Genes/Proteins	AND, GLIOBLASTOMA, MTOR, RNA
Related Diseases	Als, ALS, Cancer, glioblastoma, Glioblastoma
Related Pathways	Mtor

Pathway Diagram

graph TD
    GSPT1["GSPT1"]
    GSPT1 -->|"regulates"| Cellular_Functions["Cellular Functions"]
    GSPT1 -->|"target for"| Glioblastoma["Glioblastoma"]
    GSPT1 -->|"target for"| Als["Als"]
    GSPT1 -->|"inhibits"| Tumor["Tumor"]
    GSPT1 -->|"inhibits"| AND["AND"]
    GSPT1 -->|"inhibits"| Mtor["Mtor"]
    GSPT1 -->|"target for"| GLIOBLASTOMA["GLIOBLASTOMA"]
    YB_3_17["YB-3-17"] -->|"degrades"| GSPT1
    DDB1["DDB1"] -->|"binds"| GSPT1
    MTOR["MTOR"] -->|"inhibits"| GSPT1
    GLIOBLASTOMA -->|"target for"| GSPT1

Outgoing (18)

Target	Relation	Type	Str
Glioblastoma	associated_with	disease	0.90
Therapeutic Target	biomarker_for	biomarker	0.88
Cellular Functions	regulates	process	0.80
ALS	associated_with	disease	0.65
Glioblastoma	inhibits	disease	0.65
Glioblastoma	therapeutic_target	disease	0.65
Als	therapeutic_target	disease	0.65
Tumor	inhibits	disease	0.65
Cancer	associated_with	disease	0.65
glioblastoma	regulates	disease	0.60
glioblastoma	targets	disease	0.60
glioblastoma	inhibits	disease	0.60
GLIOBLASTOMA	therapeutic_target	gene	0.60
Mtor	inhibits	pathway	0.60
AND	inhibits	gene	0.60
MTOR	inhibits	gene	0.60
RNA	inhibits	gene	0.60
GLIOBLASTOMA	inhibits	gene	0.60

Incoming (6)

Source	Relation	Type	Str
YB-3-17	degrades	compound	0.98
YB-3-17	targets	compound	0.95
DDB1	binds	entity	0.90
MTOR	inhibits	gene	0.60
GLIOBLASTOMA	therapeutic_target	gene	0.60
rapamycin	targets	drug	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GSPT1 in their description or question text

No additional research found