gene 2,609 words KG: ZFP36L2
Contents

ZFP36L2 — Zinc Finger Protein L2

🧬 Gene Info
Gene SymbolZFP36L2
Full NameZinc Finger Protein Like 2
Chromosome12p13.31
Functionis a member of the ZFP36 family of zinc finger proteins.
Subcellular Localizations, and potentially different target RNA specificity. Some isoforms lack certain regulatory domains, which may affect the
Molecular Weight54 kDa
Amino Acids490 aa
PathwaysApoptosis
GeneCardsZFP36L2
Human Protein AtlasZFP36L2
Associated DiseasesALS
KG Connections14 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (13)

Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
Epigenetic Memory Erasure via TET2 Activation
Score: 0.74
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (7)

Neurodegeneration
disease · KG edge: implicated_in
Apoptosis in Neurodegeneration
entity · KG edge: regulates
TNF (Redirect)
redirect · KG edge: expressed_in
Tumor Necrosis Factor (TNF)
entity · KG edge: expressed_in
BCL2 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

TNF expressed_in ZFP36L2
ZFP36L2 expressed_in IL12B
BCL2 regulates ZFP36L2
ZFP36L2 regulates TNF
DMSO expressed_in ZFP36L2
ZFP36L2 associated_with ZFP36
ZFP36L2 expressed_in Ms
ZFP36L2 expressed_in Tumor
ZFP36L2 regulates APOPTOSIS
ZFP36L2 regulates Leukemia

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