| Gene Symbol | TREM1 |
| Full Name | Triggering Receptor Expressed on Myeloid Cells 1 |
| Chromosome | 6p21.1 |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Amino Acids | 234 aa |
| Exons | 5 |
| Pathways | NF-κB, MAPK pathway |
| NCBI Gene ID | 54206 |
| GeneCards | TREM1 |
| Human Protein Atlas | TREM1 |
| Extracellular domain | V-type immunoglobulin-like domain |
| Transmembrane domain | Single pass helix |
| Cytoplasmic tail | Short (5 aa) - signals through adaptor protein DAP12 |
| Associated Diseases | cognitive impairment, neurodegeneration, neuroinflammation |
| Known Drugs/Compounds | LP17 |
| Interactions | AGING, AUTOPHAGY, CD14, CD33, DAP12, LIPOPHAGY |
| KG Connections | 49 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
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