gene 1,427 words KG: TGFBI
Contents

TGFBI

🧬 Gene Info
Gene SymbolTGFBI
Full NameTransforming Growth Factor Beta Induced Protein
Chromosome5q31.1
Functionis a secreted extracellular matrix (ECM) protein that plays crucial roles in cell adhesion, tissue development, and disease pathogenesis.
Molecular Weight75 kDa
Amino Acids683 aa
Exons17
PathwaysTGF-β
UniProt IDQ15582
NCBI Gene ID7045
Ensembl IDENSG00000120708
OMIM601692
GeneCardsTGFBI
Human Protein AtlasTGFBI
Associated DiseasesAls, Ms, Schizophrenia
InteractionsCANCER, GENES
KG Connections43 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (14)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
APOE Isoform Conversion Therapy
Score: 0.72
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.56

Related Analyses (4)

Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: regulates
Genes
index · KG edge: associated_with
GJA1
gene · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
PRDM1 Gene
gene · KG edge: protects_against

Knowledge Graph (12 edges)

HCRTR2 associated_with TGFBI
GJA1 co_discussed TGFBI
TGFBI protects_against PRDM1
PRDM1 regulates TGFBI
TGFBI associated_with CD44
TGFBI associated_with GJA1
GJA1 associated_with TGFBI
CD44 associated_with TGFBI
TGFBI regulates PRDM1
PRDM1 biomarker_for TGFBI

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