gene 711 words KG: STAU2
Contents

STAU2 Gene

🧬 Gene Info
Gene SymbolSTAU2
Full NameStaufen2
Chromosome8q13.3
FunctionThis transport is essential for local protein synthesis at synapses.
Primary Expressionneural progenitor cells and regulates genes involved in neuronal differentiation and migration
PathwaysMtor Signaling
UniProt IDQ9NUR2
NCBI Gene ID27067
Ensembl IDENSG00000100095
OMIM607010
GeneCardsSTAU2
Human Protein AtlasSTAU2
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Ataxia, Dementia, frontotemporal dementia
Known Drugs/Compoundsrapamycin
InteractionsmTOR, MTOR, RNA, STAU1, STAUFEN2
KG Connections74 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (10)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Axonal RNA Transport Reconstitution
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Amyotrophic Lateral Sclerosis
redirect · KG edge: expressed_in
mTOR Signaling Dysregulation in Progressive Supranuclea
event · KG edge: expressed_in
c9orf72-als-ftd-phenotype-mechanism
general · KG edge: associated_with
C9orf72 — Chromosome 9 Open Reading Frame 72
gene · KG edge: therapeutic_target
MTOR Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

STAU2 therapeutic_target MTOR
STAU2 therapeutic_target C9ORF72
STAU2 activates Stress Granule Formation
STAU2 associated_with Spinocerebellar Ataxia Type 2
miR-217 targets STAU2
C9ORF72 associated_with STAU2
STAU2 regulates Mrna Trafficking
STAU2 activates MTOR
Rnai targets STAU2
MIR217 targets STAU2

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