| Gene Symbol | PQBP1 |
| Function | encodes a small nuclear protein that specifically binds to polyglutamine (polyQ) tracts found in various disease proteins. |
| Subcellular Localization | Nuclear |
| Molecular Weight | 37 kDa |
| Amino Acids | 312 aa |
| Pathways | Immune Response |
| Ensembl ID | ENSG00000102172 |
| GeneCards | PQBP1 |
| Human Protein Atlas | PQBP1 |
| N-terminal polyglutamine-binding domain | Recognizes expanded polyQ tracts |
| WW domain | Mediates protein-protein interactions |
| Nuclear localization signal (NLS) | Targets protein to the nucleus |
| C-terminal acidic region | Involved in transcriptional activation |
| Associated Diseases | Als, neurodegeneration |
| Interactions | AND, BRAIN INFLAMMATION, CGAS, CGAS-STING, GENES, INFLAMMATION |
| KG Connections | 27 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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