gene 924 words KG: NEK7
Contents

NEK7 Gene

🧬 Gene Info
Gene SymbolNEK7
Protein TypeSerine/Threonine Kinase
FunctionNEK7 is a 34 kDa serine/threonine kinase that plays dual roles in cell biology:
Molecular Weight34 kDa
PathwaysInflammasome
Ensembl IDENSG00000151414
GeneCardsNEK7
Human Protein AtlasNEK7
Associated DiseasesAls, Carcinoma, Encephalitis, Inflammation, Ms, Multiple Sclerosis
InteractionsA20, AMYLOID, ATP, CGAS, CGAS-STING, Cytokine
KG Connections142 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (9)

CYP46A1 Overexpression Gene Therapy
Score: 0.95
Lysosomal Enzyme Trafficking Correction
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Microbial Inflammasome Priming Prevention
Score: 0.65
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

ATP P2X3 Receptor Neurons
cell · KG edge: activates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activates
Mitochondria
entity · KG edge: activates
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: inhibits
ASC (PYCARD)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

SLC25A3 inhibits NEK7
NLRP3 interacts_with NEK7
SPR therapeutic_target NEK7
NEK7 activates NLRP3
NEK7 inhibits NLRP3
LATS1 interacts_with NEK7
NEK7 interacts_with NLRP3
BNIP3 associated_with NEK7
TLR4 associated_with NEK7
STING associated_with NEK7

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