| Gene Symbol | NDUFV2 |
| Full Name | NADH:Ubiquinone Oxidoreductase Core Subunit V2 |
| Chromosome | 25p13 |
| Protein Type | Oxidoreductase |
| Function | encodes a core subunit of mitochondrial complex I (NADH:ubiquinone oxidoreductase). |
| Primary Expression | brain tissue: - High expression in cerebral cortex - High expression in basal ganglia - Expressed in [neurons](/entities/neur |
| UniProt ID | [P23378](https://www.uniprot.org/uniprot/P23378) |
| Ensembl ID | ENSG00000170921 |
| GeneCards | NDUFV2 |
| Human Protein Atlas | NDUFV2 |
| Complex I deficiency | Documented in PD substantia nigra |
| Oxidative stress | Increased ROS from electron leak |
| Dopaminergic neuron vulnerability | Energy deficit contributes to death |
| Associated Diseases | Cancer, Lung Cancer |
| KG Connections | 17 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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