gene 1,918 words KG: MPV17
Contents

MPV17 Gene - MPV17 Mitochondrial Inner Membrane Protein

🧬 Gene Info
Gene SymbolMPV17
Protein TypeProtein
FunctionMPV17 is a mitochondrial inner membrane protein involved in mitochondrial DNA maintenance.
Molecular Weight~20 kDa
Amino Acids176 aa
UniProt IDSearch UniProt
GeneCardsMPV17
Human Protein AtlasMPV17
Multiple transmembrane helicesMPV17 contains three predicted transmembrane helices that anchor it in the mitochondrial inner membrane
N-terminal matrix-facing domainContains functional motifs important for protein interactions
Homomeric assemblyForms higher-order complexes in the inner membrane
Associated Diseasesneurodegeneration
KG Connections32 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (23)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Lysosomal Membrane Repair Enhancement
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
← Prevpg 2/2

Related Analyses (14)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Mitochondria
entity · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: expressed_in
Genes
index · KG edge: associated_with
DGUOK — Deoxyguanosine Kinase
gene · KG edge: associated_with

Knowledge Graph (12 edges)

POLG2 associated_with MPV17
SLC25A4 associated_with MPV17
MFN2 associated_with MPV17
TYMP associated_with MPV17
RRM2B associated_with MPV17
TK2 associated_with MPV17
SUCLA2 associated_with MPV17
SUCLG1 associated_with MPV17
TFAM associated_with MPV17
POLG associated_with MPV17

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