| Gene Symbol | MARK4 |
| Full Name | Microtubule Affinity Regulating Kinase 4 |
| Chromosome | 19q13.32 |
| Protein Type | Kinase |
| Function | MARK4 is a serine/threonine-protein kinase that belongs to the CAMK (Ca²⁺/calmodulin-dependent protein kinase) group and AMPK-related kinase family. |
| Primary Expression | the brain and is involved in regulating microtubule stability through tau phosphorylation |
| Subcellular Localization | Cytoplasmic, associated with microtubules |
| Molecular Weight | 76 kDa |
| Amino Acids | 659 aa |
| Pathways | AMPK, AMPK signaling |
| UniProt ID | Q96GX8 |
| NCBI Gene ID | 57731 |
| Ensembl ID | ENSG00000165548 |
| OMIM | 608285 |
| GeneCards | MARK4 |
| Human Protein Atlas | MARK4 |
| Associated Diseases | Alzheimer, Alzheimer's disease, neuroinflammation |
| Interactions | AGTR1, AND, APOPTOSIS, ATP, CANCER, C-MYC |
| KG Connections | 82 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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