| Gene Symbol | KIF23 |
| Full Name | Kinesin Family Member 23 (Mitotic Kinesin-Like Protein 1) |
| Chromosome | 15q23 |
| Protein Type | Kinesin motor protein, MKLP1 subfamily |
| Function | KIF23 (also known as MKLP1 - Mitotic Kinesin-Like Protein 1) is a plus-end directed kinesin motor protein that plays essential roles in cell division and intracellular transport. |
| Primary Expression | Ubiquitous, high in mitotic cells |
| UniProt ID | [Q9Y207](https://www.uniprot.org/uniprot/Q9Y207) |
| GeneCards | KIF23 |
| Human Protein Atlas | KIF23 |
| Cytokinesis | KIF23 forms a heterotetramer with RACGAP1 (MgcRacGAP) to form the centralspindlin complex, which is essential for cleavage furrow formation during cytokinesis |
| Microtubule organization | Regulates microtubule dynamics and organization during cell division |
| Vesicle transport | Involved in intracellular trafficking of vesicles and organelles |
| Neuronal function | Expressed in neurons where it may contribute to: |
| RACGAP1 | forms the centralspindlin complex |
| EVI5 | regulates cytokinesis |
| Associated Diseases | neurodegeneration |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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