gene 953 words KG: KCND2
Contents

KCND2 Gene - Kv4.2 Voltage-Gated Potassium Channel

🧬 Gene Info
Gene SymbolKCND2
Full NamePotassium Voltage-Gated Channel Subfamily D Member 2
AliasesKv4.2, Kv4.2 Potassium Channel
Chromosome7q31.2
Functionof 647 amino acids
Subcellular Localizationdendritic shafts where they shape excitatory postsynaptic potentials, regulate backpropagation of action potentials, and
Molecular Weight72 kDa
Amino Acids647 aa
Exons7
PathwaysEffect
UniProt IDQ9NZV8
NCBI Gene ID8936
Ensembl IDENSG00000163637
OMIM605721
GeneCardsKCND2
Human Protein AtlasKCND2
Associated Diseasesepilepsy, glioblastoma
InteractionsAND, CANCER, EPILEPSY, GBM, GLIOBLASTOMA, NEURON
KG Connections31 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

See Also (3)

NeuRon Therapeutics
company · KG edge: activates
Oligodendrocyte-Myelin Dysfunction Validation in Parkin
experiment · KG edge: activates
GLI Gene Family
gene · KG edge: activates

Knowledge Graph (12 edges)

GBM activates KCND2
KCND2 modulates Neuronal Excitability
KCND2 expressed_in Oligodendrocyte Progenitor Cells
KCND2 encodes Potassium Ion Channel
Oligodendrocyte Progenitor Cell expressed_in KCND2
KCND2 activates GBM
KCND2 associated_with Opc
KCND2 interacts_with epilepsy
KCND2 enhances neuronal excitability
GBM co_expressed_with KCND2

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.