gene 657 words KG: EWSR1
Contents

EWSR1 Gene

🧬 Gene Info
Gene SymbolEWSR1
Full NameEwing Sarcoma Breakpoint Region 1
Chromosome22q12.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight68.5 kDa
Amino Acids655 aa
Exons17
Pathwaysoxidative stress response
UniProt IDQ01844
NCBI Gene ID2130
Ensembl IDENSG00000182944
OMIM133450
GeneCardsEWSR1
Human Protein AtlasEWSR1
Exon 1-7Encodes the N-terminal transactivation domain (QSY-rich)
Associated DiseasesALS
InteractionsAND, CANCER, FRMD4A, FUS, P53, PKM2
KG Connections44 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (10)

Cross-Seeding Prevention Strategy
Score: 0.69
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Axonal RNA Transport Reconstitution
Score: 0.70

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Apoptosis in Neurodegeneration
entity · KG edge: therapeutic_target
DDIT3 Gene
gene · KG edge: associated_with
G3BP1
gene · KG edge: therapeutic_target
HSPA1A Gene
gene · KG edge: therapeutic_target
MECP2 — Methyl-CpG Binding Protein 2
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

TAF15 associated_with EWSR1
FUS associated_with EWSR1
EWSR1 associated_with DDIT3
IGF2BP1 therapeutic_target EWSR1
EWSR1 therapeutic_target YBX1
EWSR1 therapeutic_target MECP2
EWSR1 therapeutic_target HSPA1A
EWSR1 therapeutic_target SYNCRIP
EWSR1 therapeutic_target G3BP1
EWSR1 associated_with circFRMD4A

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