gene 983 words KG: DDX60
Contents

DDX60 — DEAD-Box Helicase 60

🧬 Gene Info
Gene SymbolDDX60
Full NameDEAD-Box Helicase 60
Chromosome4q33
Functionis an RNA helicase involved in antiviral immunity and RNA metabolism.
GeneCardsDDX60
Human Protein AtlasDDX60
DEAD Box CoreThe central helicase domain containing the conserved motifs (Q-motif, motifs I-VI) responsible for ATP hydrolysis and RNA unwinding [@fairmanwilliams2010]
LRR DomainLeucine-rich repeat region at the N-terminus, potentially involved in protein-protein interactions and RNA binding [@moy2009]
C-terminal DomainInvolved in substrate specificity and interaction with signaling partners
Associated Diseasesneurodegeneration
InteractionsAKT, IFN, KRAS, RNA, STAT3
KG Connections10 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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