gene 778 words KG: DCTN5
Contents

DCTN5 Gene

🧬 Gene Info
Gene SymbolDCTN5
Chromosome16p12.2
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionSpinal Cord
PathwaysMitophagy, Alpha-Synuclein
GeneCardsDCTN5
Human Protein AtlasDCTN5
Associated DiseasesALS, Neurodegeneration, Parkinson
InteractionsAlpha-Synuclein, DAPK1, DCAF17, H2AX, MITOPHAGY, P62
KG Connections44 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
TREM2-mediated microglial tau clearance enhancement
Score: 0.62

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (9)

Parkinson Basal Ganglia Circuit
circuit · KG edge: causes
Neurodegeneration
disease · KG edge: causes
PINK1 (PTEN-Induced Kinase 1)
entity · KG edge: inhibits
DAPK1 Gene
gene · KG edge: activates
DCAF17 Gene - DDB1 and CUL4 Associated Factor 17
gene · KG edge: activates

Knowledge Graph (12 edges)

DCTN5 associated_with TREM2
DCTN5 associated_with OxPC
DCTN5 associated_with STRRIDE
DAPK1 activates DCTN5
DCTN5 activates DCAF17
DCTN5 inhibits UBIQUITIN
DCTN5 inhibits PINK1
DCTN5 inhibits H2AX
DCTN5 inhibits P62
DCTN5 activates SNCA

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