gene 1,299 words KG: CDC25B
Contents

CDC25B Gene

🧬 Gene Info
Gene SymbolCDC25B
Chromosome20p13
Protein TypePhosphatase
Functionis a dual-specificity protein phosphatase that plays a critical role in regulating cell cycle progression by removing inhibitory phosphates from cyclin-dependent kinases (CDKs)[@cdc2021].
Primary Expressionvarious cancers:
Subcellular Localization**: Nuclear import/export controls
Molecular Weight72 kDa
Amino Acids647 aa
GeneCardsCDC25B
Human Protein AtlasCDC25B
Proliferating cellsHigh expression in dividing cells
BrainLow expression in normal adult brain, upregulated in disease states
TestisHigh expression in spermatogenesis
Embryonic tissuesWidespread expression during development
Cytoplasmic localizationInactive state during interphase
Associated Diseasesneurodegeneration
Known Drugs/Compoundsfarrerol, menadione
InteractionsCdc2, PKCδ
KG Connections22 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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