| Gene Symbol | CD63 |
| Aliases | LAMP-3 |
| Chromosome | 12q13.2 |
| Function | is a member of the tetraspanin superfamily that plays crucial roles in membrane trafficking, lysosomal function, and exosome biogenesis. |
| Primary Expression | intracellular vesicles, including lysosomes, endosomes, and secretory granules[@matila1995][@tomlinson1999] |
| Subcellular Localization | CD63 primarily localizes to lysosomes (primary storage compartment), late endosomes (multivesicular body formation), sec |
| Amino Acids | 238 aa |
| Exons | 7 |
| Pathways | oxidative stress response, phagocytosis, unfolded protein response |
| Ensembl ID | ENSG00000135404 |
| GeneCards | CD63 |
| Human Protein Atlas | CD63 |
| Associated Diseases | Als |
| Interactions | Actin, ALZHEIMER, AMYLOID, AND, APOE, App |
| KG Connections | 103 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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