Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FN1B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | FN1B |
| Key Genes/Proteins | AGING, ALZHEIMER'S DISEASE, FN1 |
| Related Diseases | Aging, Als, Alzheimer, Dementia, Ms |
| Related Pathways | Blood-Brain Barrier |
graph TD
FN1B[FN1B]
FN1B -->|inhibits| gliosis[gliosis]
FN1B -->|activates| gliovascular_remodeling[gliovascular remodeling]
FN1B -->|activates| microglial_response[microglial response]
FN1B -.protects against.-> Alzheimer[Alzheimer]
FN1B -.protects against.-> Aging[Aging]
FN1B -.protects against.-> Als[Als]
FN1B -.protects against.-> Ms[Ms]
FN1B -.protects against.-> Dementia[Dementia]
FN1B -.protects against.-> ALZHEIMER_S_DISEASE[ALZHEIMER'S DISEASE]
FN1B -.protects against.-> Blood_Brain_Barrier[Blood-Brain Barrier]
AGING[AGING] -.protects against.-> FN1B
benchmark_ot_ad_answer_key_FN1[benchmark_ot_ad_answer_key:FN1B] -->|data_in| FN1B| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:FN1B | data_in | dataset_row | 0.00 |
| gliosis | inhibits | phenotype | 0.80 |
| gliovascular remodeling | activates | phenotype | 0.80 |
| microglial response | activates | phenotype | 0.80 |
| Alzheimer | protects_against | disease | 0.65 |
| Aging | protects_against | disease | 0.65 |
| Als | protects_against | disease | 0.65 |
| Ms | protects_against | disease | 0.65 |
| Dementia | protects_against | disease | 0.65 |
| FN1 | associated_with | gene | 0.60 |
| ALZHEIMER'S DISEASE | protects_against | gene | 0.60 |
| Blood-Brain Barrier | protects_against | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:FN1B | data_in | dataset_row | 0.00 |
| AGING | protects_against | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning FN1B in their description or question text
No additional research found