Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DLBCL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | DLBCL |
| Key Genes/Proteins | ACO1, ATM, BCR, BRD4, KIF2A, LPIN1 |
| Related Diseases | Heterogeneity |
| Related Pathways | BCR_SIGNALLING |
graph TD
DLBCL[DLBCL]
OST_B[OST-B] -->|target for| DLBCL
Btk_Inhibitors[Btk Inhibitors] -->|treats| DLBCL
MT1G[MT1G] -.biomarker for.-> DLBCL
MTOR[MTOR] -.biomarker for.-> DLBCL
BRD4[BRD4] -.biomarker for.-> DLBCL
ACO1[ACO1] -.biomarker for.-> DLBCL
PEBP1[PEBP1] -.biomarker for.-> DLBCL
LPIN1[LPIN1] -.biomarker for.-> DLBCL
ATM[ATM] -.biomarker for.-> DLBCL
PRDX1[PRDX1] -.biomarker for.-> DLBCL| Target | Relation | Type | Str |
|---|---|---|---|
| Heterogeneity | associated_with | phenotype | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| OST-B | therapeutic_target | protein | 0.90 |
| Btk Inhibitors | treats | drug | 0.90 |
| MTOR | biomarker_for | gene | 0.80 |
| BRD4 | biomarker_for | gene | 0.80 |
| ACO1 | biomarker_for | gene | 0.80 |
| PEBP1 | biomarker_for | gene | 0.80 |
| LPIN1 | biomarker_for | gene | 0.80 |
| ATM | biomarker_for | gene | 0.80 |
| KIF2A | associated_with | gene | 0.80 |
| PRDX1 | biomarker_for | gene | 0.80 |
| MT1G | biomarker_for | gene | 0.80 |
| SAT1 | biomarker_for | gene | 0.80 |
| SRXN1 | biomarker_for | gene | 0.80 |
| BCR_SIGNALLING | treats | pathway | 0.56 |
| BCR | associated_with | protein | 0.56 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning DLBCL in their description or question text
No additional research found