| Younger average age | Often spouse caregivers in their 60s-70s, but also adult children |
| Female predominance | Approximately 60-70% of primary caregivers are female |
| Employment impact | Many caregivers reduce work hours or leave employment |
| Geographic isolation | Rural caregivers face additional access challenges |
| Mobility assistance | Transferring patients, fall prevention |
| Activities of daily living | Bathing, dressing, feeding assistance |
| 24-hour supervision | Safety monitoring, especially due to impulsivity |
| Medication management | Complex regimens, monitoring responses |
| Sleep disruption | Caregivers often lose sleep due to patient nighttime agitation |
| Chronic stress | Sustained high stress levels over disease course |
| Depression | High prevalence among CBS caregivers (30-50%) |
| Anxiety | About disease progression, caregiver's own health |
| KG Connections | 1 knowledge graph edges |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
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