gene 726 words KG: DOCK3
Contents

DOCK3 - Dedicator of Cytokinesis 3

🧬 Gene Info
Gene SymbolDOCK3
Full NameDedicator of Cytokinesis 3
AliasesPage for DOCK3, Page for DOCK3 Protein
Chromosome3p21.2
FunctionRac1 Activation: DOCK3 activates Rac1, a key regulator of actin cytoskeleton dynamics [2]
Primary ExpressionCerebral cortex, Hippocampus, Motor neurons, Spinal cord
Molecular Weight220 kDa
PathwaysPI3K, PI3K signaling, Wnt Signaling
UniProt IDQ9UPJ4
NCBI Gene ID1786
Ensembl IDENSG00000157617
OMIM607337
GeneCardsDOCK3
Human Protein AtlasDOCK3
Associated DiseasesAmyotrophic Lateral Sclerosis, Parkinson's Disease, Neurodegeneration
InteractionsALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, APP, APP/PS1, ERBB4
KG Connections19 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

NLRP3 activates DOCK3
TLR4 activates DOCK3
DOCK3 activates SIRT3
DOCK3 activates ERBB4
DOCK3 activates APP
ErbB4 upstream_of DOCK3
DOCK3 activates NF-ΚB
DOCK3 activates INFLAMMATION
DOCK3 activates NEUROINFLAMMATION
DOCK3 activates Neuroinflammation

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