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clinical 1,167 words KG: PD
Contents

AB-1005 (REGENERATE-PD) GDNF Gene Therapy Trial

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Knowledge Graph

Related Hypotheses (26)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.92CYP46A1 Overexpression Gene Therapy
Score: 0.92Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.85Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76

Related Analyses (17)

Synaptic pruning by microglia in early AD
neurodegeneration · archivedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedEpigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archivedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedAPOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived

Related Experiments (14)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Longitudinal TLR2 reporter gene study in α-synuclein mice
validation · proposed · Score: 0.90Acteoside treatment in LPS-induced SALI mouse model
validation · proposed · Score: 0.90Leukocyte gene expression analysis in COVID-19 patients
exploratory · proposed · Score: 0.90RBG treatment in ApoE-/- atherosclerosis mouse model
validation · proposed · Score: 0.90

See Also (11)

GBA1 (Redirect)
redirect · KG edge: causesDNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: implicated_inABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: implicated_inAPOB Gene
gene · KG edge: implicated_inCNTNAP4 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PD causes NEURODEGENERATION
PD causes DOPAMINERGIC_NEURONS
PD causes neurodegeneration
NEUROTROPHINS treats PD
AGE associated_with PD
SNCA causes PD
LRRK2 causes PD
GBA1 causes PD
PRKN causes PD
PINK1 causes PD

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