gene 1,548 words KG: CNTNAP4
Contents

CNTNAP4 Gene

🧬 Gene Info
Gene SymbolContactin-Associated Protein 4
Chromosome16q23.3
Protein TypeNeurexin family cell adhesion molecule
Functionis a member of the neurexin family of transmembrane adhesion proteins.
Primary ExpressionBrain (cortex, hippocampus, cerebellum), spinal cord
PathwaysComplement, SNCA Pathology
UniProt IDQ9C0A0
NCBI Gene ID12925
Ensembl IDENSG00000171804
OMIM610610
Contactin domainEnables homophilic and heterophilic interactions with other CNTNAP proteins
Neurexin repeat domainsSupport protein-protein interactions at the synaptic cleft
FFC domainFound in fibrinogen-related proteins, involved in carbohydrate binding
PDZ-binding motifInteracts with PDZ domain-containing scaffolding proteins
Proline-rich regionPotential protein interaction site
Associated DiseasesAutism, Parkinson, PD
InteractionsC1Q, MICROGLIA, NEURON, Rb
KG Connections62 knowledge graph edges
DatabasesGeneCardsHPASTRING

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