| Gene Symbol | CIITA |
| Chromosome | 16p13.13 |
| Protein Type | Transcriptional coactivator |
| Function | ### MHC Class II Expression |
| Primary Expression | non-immune cells: - Endothelial cells: Can express MHC class II in response to IFN-γ - Tumor cells: Sometimes expressed in cancer cells - Ne |
| Molecular Weight | 125 kDa |
| Amino Acids | 1130 aa |
| Pathways | Autophagy, Immune Response, Inflammasome, Mitophagy |
| UniProt ID | P33076 |
| NCBI Gene ID | 4261 |
| Ensembl ID | ENSG00000179583 |
| GeneCards | CIITA |
| Human Protein Atlas | CIITA |
| N-terminal acidic domain | Mediates interactions with transcriptional coactivators and chromatin remodelers |
| Associated Diseases | neurodegeneration |
| Interactions | AND, CANCER, CD8, CHIP, CREB1, DNA |
| KG Connections | 59 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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