| Gene Symbol | NPY |
| Full Name | Y1 Receptor Neurons |
| Chromosome | 7p15.1 |
| Function | The NPY gene encodes a prepropeptide that undergoes proteolytic processing to yield the mature NPY peptide. |
| Primary Expression | hippocampus, Hypothalamus, Brainstem, Thalamus, Amygdala |
| Amino Acids | 36 aa |
| Pathways | Er Stress, Mtor, Lipid Metabolism, Autophagy, Akt |
| Ensembl ID | ENSG00000157240 |
| GeneCards | NPY |
| Human Protein Atlas | NPY |
| Hypothalamus | Particularly in the arcuate nucleus (ARC), paraventricular nucleus (PVN), and lateral hypothalamus, where they regulate feeding and energy balance |
| Amygdala | Central nucleus and basolateral amygdala, involved in emotional processing and anxiety |
| Cortex | Prefrontal cortex and piriform cortex, participating in cognitive functions |
| Hippocampus | Dentate gyrus and CA regions, implicated in memory and neuroprotection |
| Thalamus | Paraventricular nucleus, involved in stress responses |
| Associated Diseases | Als, Alzheimer, Alzheimer's disease, amyotrophic lateral sclerosis |
| Interactions | ABCA7, ADCY2, AIF1, AKT, Albumin, ALZHEIMER |
| KG Connections | 304 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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