cell 518 words KG: microglia
Contents

Microglia State Index

🧫 Cell Type Info
Cell Typemicroglia
Associated DiseasesAlzheimer's disease, cardiovascular diseases, neurodegeneration, neuroinflammation, stroke
Related GenesALS, BDNF, C3, CD33
Linked Hypotheses398 hypotheses

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Knowledge Graph

Related Hypotheses (30)

Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
TREM2-mediated microglial tau clearance enhancement
Score: 0.59
TREM2-Dependent Microglial Senescence Transition
Score: 0.95

Related Analyses (30)

Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · completed
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived

Related Experiments (19)

VSMC cholesterol efflux and P2RY12 signaling
exploratory · proposed · Score: 0.90
P2RY12 inhibition in atherosclerosis mouse model
validation · proposed · Score: 0.90
P2RY12 regulation of autophagy in VSMCs
exploratory · proposed · Score: 0.90
TREM2 Function in Alzheimer's Disease — From Risk Variant to
validation · proposed · Score: 0.45
Microglial TREM2 Agonist In Vivo Efficacy
validation · proposed · Score: 0.45

See Also (2)

ABCA7 (Redirect)
redirect · KG edge: associated_with
ABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: activates

Knowledge Graph (12 edges)

VCP associated_with microglia
mBDNF associated_with microglia
microglia associated_with BDNF
EGFR expresses microglia
GRN associated_with microglia
BIN1 associated_with microglia
CLU associated_with microglia
GFP associated_with microglia
ABCA1 associated_with microglia
GDNF associated_with microglia

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