| Gene Symbol | NEUROFILAMENT LIGHT CHAIN |
| Molecular Weight | 61.5 kDa |
| Amino Acids | 543 aa |
| NfL (Light chain, 61 kDa) | The smallest subunit, essential for filament assembly |
| NfM (Medium chain, 95 kDa) | Phosphorylated on serine residues in the tail domain |
| NfH (Heavy chain, 200 kDa) | Heavily phosphorylated, regulates axonal caliber |
| Associated Diseases | Amyotrophic Lateral Sclerosis, Multiple Sclerosis |
| Interactions | AMYLOID, IL10, IL18, PHOSPHORYLATED TAU |
| KG Connections | 16 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!