Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BATF3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | BATF3 |
| Key Genes/Proteins | Actin, AND, AP-1, App, CANCER, CD8 |
| Related Diseases | Als, ALS, Cancer |
| Related Pathways | Epigenetic |
graph TD
BATF3["BATF3"]
BATF3 -->|"activates"| CAR_T_Cell_Clonal_Expansion["CAR T Cell Clonal Expansion"]
BATF3 -->|"activates"| CAR_T_CELL_EXPANSION["CAR T CELL EXPANSION"]
BATF3 -->|"activates"| CAR_T_Cell_Expansion["CAR T Cell Expansion"]
BATF3 -->|"activates"| MYC["MYC"]
BATF3 -->|"activates"| Cancer["Cancer"]
BATF3 -->|"activates"| ALS["ALS"]
BATF3 -->|"activates"| Tumor["Tumor"]
BATF3 -->|"activates"| Als["Als"]
TET2["TET2"] -->|"regulates"| BATF3
MYC -->|"expressed in"| BATF3
CD8["CD8"] -->|"activates"| BATF3
RIPK1["RIPK1"] -->|"activates"| BATF3
RIPK3["RIPK3"] -->|"activates"| BATF3
CANCER["CANCER"] -->|"activates"| BATF3
JUN["JUN"] -->|"activates"| BATF3| Target | Relation | Type | Str |
|---|---|---|---|
| CAR T Cell Clonal Expansion | activates | process | 0.92 |
| CAR T cell proliferation | drives | process | 0.90 |
| Car T Cell Clonal Expansion | promotes | process | 0.90 |
| CAR T CELL EXPANSION | activates | entity | 0.90 |
| CAR T Cell Expansion | activates | process | 0.85 |
| MYC | activates | gene | 0.82 |
| AP-1 | interacts_with | protein | 0.80 |
| Als | activates | disease | 0.65 |
| Tumor | activates | disease | 0.65 |
| Cancer | activates | disease | 0.65 |
| ALS | activates | disease | 0.65 |
| AND | activates | gene | 0.60 |
| CANCER | activates | gene | 0.60 |
| Epigenetic | activates | pathway | 0.60 |
| JUN | activates | gene | 0.60 |
| RIPK3 | activates | gene | 0.60 |
| Actin | activates | protein | 0.60 |
| MYC | causes | gene | 0.60 |
| TET2 | causes | gene | 0.60 |
| TET2 | activates | gene | 0.60 |
| T cells | expressed_in | cell_type | 0.60 |
| Necroptosis | activates | pathway | 0.60 |
| Immune Response | activates | pathway | 0.60 |
| T Cell | activates | cell_type | 0.60 |
| CD8 | activates | gene | 0.60 |
| App | activates | protein | 0.60 |
| T Cell | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning BATF3 in their description or question text
No additional research found