| Gene Symbol | ATG2A |
| Full Name | Autophagy Related 2A |
| Chromosome | 11q13.2 |
| Protein Type | Peripheral Membrane Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | the autophagosomal membrane |
| Molecular Weight | 206 kDa |
| UniProt ID | [Q9BSB5](https://www.uniprot.org/uniprot/Q9BSB5) |
| GeneCards | ATG2A |
| Human Protein Atlas | ATG2A |
| Membrane tethering | ATG2A bridges the growing autophagosome (phagophore) with ER-derived membranes |
| Lipid transfer | ATG2A functions as a lipid transfer protein (LTP), mediating phospholipid delivery from ER to autophagosomal membranes |
| WIPI proteins | ATG2A interacts with WIPI1/2/3/4 (WD repeat domain phosphoinositide-interacting proteins) to localize to the autophagosomal membrane |
| Associated Diseases | Brain Atrophy, developmental_regression, Developmental Regression, epilepsy, neurodegeneration |
| Interactions | AUTOPHAGY, FERROPTOSIS, LC3B, MITOCHONDRIA, NEURODEGENERATION, WDR45 |
| KG Connections | 44 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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