concept

PHOSPHATIDYLETHANOLAMINE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PHOSPHATIDYLETHANOLAMINE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

13Connections

0Hypotheses

0Analyses

8Outgoing

5Incoming

0Experiments

0Debates

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💡 Concept Info

Name	PHOSPHATIDYLETHANOLAMINE
Key Genes/Proteins	ACSL4

Pathway Diagram

graph TD
    PHOSPHATIDYLETHANOLAMINE[PHOSPHATIDYLETHANOLAMINE]
    PHOSPHATIDYLETHANOLAMINE -->|involved_in| neuronal_function[neuronal function]
    PHOSPHATIDYLETHANOLAMINE -->|expressed in| mitochondrial_membrane[mitochondrial membrane]
    PHOSPHATIDYLETHANOLAMINE -->|contributes to| Ferroptosis[Ferroptosis]
    PHOSPHATIDYLETHANOLAMINE -->|expressed in| plasma_membrane[plasma membrane]
    PHOSPHATIDYLETHANOLAMINE -->|implicated in| Alzheimer_s_Disease[Alzheimer's Disease]
    PHOSPHATIDYLETHANOLAMINE -->|implicated in| Parkinson_s_Disease[Parkinson's Disease]
    PHOSPHATIDYLETHANOLAMINE -->|implicated in| hereditary_spastic_paraplegia[hereditary spastic paraplegia]
    ATG8[ATG8] -->|binds| PHOSPHATIDYLETHANOLAMINE
    ACSL4[ACSL4] -->|acylates| PHOSPHATIDYLETHANOLAMINE
    phosphatidylserine[phosphatidylserine] -->|mediates| PHOSPHATIDYLETHANOLAMINE
    cytidine_diphosphate_ethanolam[cytidine diphosphate-ethanolamine pathway] -->|mediates| PHOSPHATIDYLETHANOLAMINE
    ATG2A[ATG2A] -->|regulates| PHOSPHATIDYLETHANOLAMINE

Outgoing (8)

Target	Relation	Type	Str
mitochondrial integrity	associated_with	process	0.95
mitochondrial membrane	expressed_in	cell_type	0.90
neuronal function	involved_in	process	0.90
Ferroptosis	contributes_to	process	0.89
plasma membrane	expressed_in	cell_type	0.85
Parkinson's Disease	implicated_in	disease	0.80
Alzheimer's Disease	implicated_in	disease	0.80
hereditary spastic paraplegia	implicated_in	disease	0.75

Incoming (5)

Source	Relation	Type	Str
ATG8	binds	protein	0.95
ACSL4	acylates	gene	0.90
phosphatidylserine	mediates	compound	0.85
cytidine diphosphate-ethanolamine pathway	mediates	pathway	0.80
ATG2A	regulates	protein	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PHOSPHATIDYLETHANOLAMINE in their description or question text

No additional research found