Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEURONAL FUNCTION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEURONAL FUNCTION |
| Key Genes/Proteins | ALZHEIMER DISEASE |
graph TD
NEURONAL_FUNCTION["NEURONAL FUNCTION"]
M6A_Modification["M6A Modification"] -->|"modulates"| NEURONAL_FUNCTION
Glia["Glia"] -->|"involved_in"| NEURONAL_FUNCTION
Blood_Brain_Barrier["Blood-Brain Barrier"] -->|"involved_in"| NEURONAL_FUNCTION
Genome_Maintenance["Genome Maintenance"] -->|"involved_in"| NEURONAL_FUNCTION
MAPT["MAPT"] -->|"involved_in"| NEURONAL_FUNCTION
Mitochondrial_Dysfunction["Mitochondrial Dysfunction"] -->|"regulates"| NEURONAL_FUNCTION
Mitochondrial_Health["Mitochondrial Health"] -->|"involved_in"| NEURONAL_FUNCTION| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| M6A Modification | modulates | mechanism | 0.95 |
| Astrocytes | associated_with | cell_type | 0.95 |
| Genome Maintenance | involved_in | process | 0.90 |
| MAPT | involved_in | protein | 0.90 |
| Glia | involved_in | cell_type | 0.90 |
| glia | associated_with | cell_type | 0.90 |
| phosphatidylethanolamine | involved_in | compound | 0.90 |
| Blood-Brain Barrier | involved_in | cell_type | 0.90 |
| Amyloid-Beta | inhibits | protein | 0.88 |
| Proteasome Dysfunction | inhibits | process | 0.88 |
| Mitochondrial Dysfunction | regulates | process | 0.88 |
| lipid metabolism dysregulation | associated_with | process | 0.85 |
| Glia | regulates | cell_type | 0.85 |
| Mitochondrial Health | involved_in | phenotype | 0.85 |
| MTOR | involved_in | pathway | 0.85 |
| Jak/Stat | regulates | pathway | 0.85 |
| Jak/Stat Signaling | regulates | pathway | 0.80 |
| Protein Arginine Methyltransferases | regulates | protein | 0.80 |
| Unc13A | involved_in | protein | 0.78 |
| arginine methylation | modulates | process | 0.75 |
| Labile Microtubule Fraction | involved_in | phenotype | 0.75 |
| Stable Microtubule Fraction | involved_in | phenotype | 0.75 |
| PRMT1 | regulates | entity | 0.75 |
| PRMT5 | regulates | entity | 0.75 |
| PIKFYVE | regulates | protein | 0.75 |
| HNRNP | regulates | protein | 0.75 |
| APOE4 | associated_with | gene | 0.70 |
| ALZHEIMER DISEASE | disrupts | gene | 0.60 |
| GBA | involved_in | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NEURONAL FUNCTION in their description or question text
No additional research found