Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEURODEVELOPMENTAL DISORDERS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEURODEVELOPMENTAL DISORDERS |
graph TD
NEURODEVELOPMENTAL_DISORDERS[NEURODEVELOPMENTAL DISORDERS]
Autophagy[Autophagy] -->|involved_in| NEURODEVELOPMENTAL_DISORDERS
HNRNP[HNRNP] -->|causes| NEURODEVELOPMENTAL_DISORDERS
SWI_SNF[SWI/SNF] -->|causes| NEURODEVELOPMENTAL_DISORDERS
IGF2[IGF2] -->|target for| NEURODEVELOPMENTAL_DISORDERS
Hnrnp_Gene_Mutations[Hnrnp Gene Mutations] -.biomarker for.-> NEURODEVELOPMENTAL_DISORDERS
CHROMATINOPATHY_GENES[CHROMATINOPATHY GENES] -->|causes| NEURODEVELOPMENTAL_DISORDERS
stress_granule_accumulation[stress granule accumulation] -->|contributes to| NEURODEVELOPMENTAL_DISORDERS
HDAC3[HDAC3] -->|target for| NEURODEVELOPMENTAL_DISORDERS| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| HNRNP | causes | gene | 0.95 |
| Autophagy | involved_in | process | 0.95 |
| HNRNP | risk_factor_for | gene | 0.90 |
| SWI/SNF | causes | protein | 0.90 |
| IGF2 | therapeutic_target | protein | 0.90 |
| Hnrnp Gene Mutations | biomarker_for | biomarker | 0.88 |
| AUTOPHAGY-RELATED GENES | associated_with | gene | 0.88 |
| CHROMATINOPATHY GENES | causes | gene | 0.87 |
| IGF2 | treats | protein | 0.85 |
| RAS superfamily | associated_with | protein | 0.85 |
| stress granule accumulation | contributes_to | process | 0.85 |
| HDAC3 | therapeutic_target | gene | 0.80 |
| RHOA | implicated_in | gene | 0.70 |
| RAS | implicated_in | gene | 0.70 |
| RAC | implicated_in | gene | 0.70 |
| SQSTM1 | associated_with | gene | 0.70 |
| SRPK1 | implicated_in | gene | 0.60 |
| SGMS1 | implicated_in | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NEURODEVELOPMENTAL DISORDERS in their description or question text
No additional research found