gene

ZFP36L2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ZFP36L2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections

0Hypotheses

0Analyses

10Outgoing

4Incoming

0Experiments

0Debates

Summary

ZFP36L2 (Zinc Finger Protein Like 2) encodes an RNA-binding protein involved in post-transcriptional gene regulation, mRNA decay, and cell cycle control

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🧬 Gene Info

Gene Symbol	ZFP36L2
Full Name	Zinc Finger Protein Like 2
Chromosome	12p13.31
Function	is a member of the ZFP36 family of zinc finger proteins.
Subcellular Localization	s, and potentially different target RNA specificity. Some isoforms lack certain regulatory domains, which may affect the
Molecular Weight	54 kDa
Amino Acids	490 aa
Pathways	Apoptosis
GeneCards	ZFP36L2
Human Protein Atlas	ZFP36L2
Associated Diseases	ALS
KG Connections	14 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ZFP36L2 — Zinc Finger Protein L2

gene · 2609 words

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Pathway Diagram

graph TD
    ZFP36L2["ZFP36L2"]
    Ms{"Ms"}
    ZFP36L2 -->|"expressed in"| Ms
    Tumor{"Tumor"}
    ZFP36L2 -->|"expressed in"| Tumor
    Leukemia{"Leukemia"}
    ZFP36L2 -->|"regulates"| Leukemia
    ZFP36["ZFP36"]
    ZFP36L2 -->|"associated with"| ZFP36
    IL12B["IL12B"]
    ZFP36L2 -->|"expressed in"| IL12B
    APOPTOSIS["APOPTOSIS"]
    ZFP36L2 -->|"regulates"| APOPTOSIS
    Apoptosis(["Apoptosis"])
    ZFP36L2 -->|"regulates"| Apoptosis
    neurodegeneration["neurodegeneration"]
    ZFP36L2 -->|"implicated in"| neurodegeneration
    DMSO["DMSO"]
    DMSO -->|"expressed in"| ZFP36L2
    TNF["TNF"]
    TNF -->|"expressed in"| ZFP36L2
    BCL2["BCL2"]
    BCL2 -->|"regulates"| ZFP36L2
    style ZFP36L2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (10)

Target	Relation	Type	Str
Leukemia	regulates	disease	0.65
Ms	expressed_in	disease	0.65
Tumor	expressed_in	disease	0.65
ALS	associated_with	disease	0.65
Immune Response	regulates	pathway	0.60
TNF	regulates	gene	0.60
APOPTOSIS	regulates	gene	0.60
Apoptosis	regulates	pathway	0.60
IL12B	expressed_in	gene	0.60
ZFP36	associated_with	gene	0.60

Incoming (4)

Source	Relation	Type	Str
TNF	expressed_in	gene	0.60
BCL2	regulates	gene	0.60
ZFP36	associated_with	gene	0.60
DMSO	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ZFP36L2 in their description or question text

No additional research found