Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ZDHHC7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ZDHHC7 |
| Key Genes/Proteins | ATG, ATG12, ATG16L1, ATG5, AUTOPHAGY, BACE1 |
| Related Pathways | Autophagy |
graph TD
ZDHHC7["ZDHHC7"]
ZDHHC7 -->|"modulates"| ATG16L1["ATG16L1"]
ZDHHC7 -->|"interacts"| MAP1LC3["MAP1LC3"]
ZDHHC7 -->|"interacts"| Autophagy["Autophagy"]
ZDHHC7 -->|"interacts"| ATG12["ATG12"]
ZDHHC7 -->|"interacts"| UBIQUITIN["UBIQUITIN"]
ZDHHC7 -->|"interacts"| ATG5["ATG5"]
ZDHHC7 -->|"interacts"| LC3["LC3"]
LC3 -->|"interacts"| ZDHHC7
ATG16L1 -->|"interacts"| ZDHHC7
AUTOPHAGY["AUTOPHAGY"] -->|"interacts"| ZDHHC7
ATG5 -->|"interacts"| ZDHHC7
ATG["ATG"] -->|"interacts"| ZDHHC7
UBIQUITIN -->|"interacts"| ZDHHC7
ATG12 -->|"interacts"| ZDHHC7
AND["AND"] -->|"interacts"| ZDHHC7| Source | Relation | Type | Str |
|---|---|---|---|
| LC3 | interacts_with | gene | 0.60 |
| ATG16L1 | interacts_with | gene | 0.60 |
| AUTOPHAGY | interacts_with | gene | 0.60 |
| ATG5 | interacts_with | gene | 0.60 |
| ATG | interacts_with | gene | 0.60 |
| UBIQUITIN | interacts_with | gene | 0.60 |
| ATG12 | interacts_with | gene | 0.60 |
| BACE1 | associated_with | gene | 0.55 |
| BACE1 | activates | gene | 0.55 |
| BACE1 | biomarker_for | gene | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ZDHHC7 in their description or question text
No additional research found