Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ZDHHC13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
ZDHHC13 is a gene implicated in neurodegeneration research. Key relationships include: activates, implicated in. Associated with Als. Connected to 11 entities in the SciDEX knowledge graph.
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| Gene Symbol | ZDHHC13 |
| Full Name | Zinc Finger DHHC-Type Containing 13 |
| Chromosome | 2p22.2 |
| Protein Type | Acyltransferase, palmitoyltransferase |
| Function | is a member of the zinc finger DHHC domain-containing protein family, also known as the palmitoyltransferase (PAT) family. |
| Primary Expression | Cortex, Hippocampus, Cerebellum, Hair follicles |
| Molecular Weight | 56 kDa |
| Amino Acids | 512 aa |
| Pathways | Autophagy |
| UniProt ID | [Q7RTP6](https://www.uniprot.org/uniprot/Q7RTP6) |
| GeneCards | ZDHHC13 |
| Human Protein Atlas | ZDHHC13 |
| Associated Diseases | neurodegeneration |
| Interactions | ATG, ATG101, ATG13, ATG14L, AUTOPHAGY, FIP200 |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["ZDHHC13"]
N1["Als"]
N0 -->|"activates"| N1
N2["AUTOPHAGY"]
N0 -->|"activates"| N2
N3["LYSOSOME"]
N0 -->|"activates"| N3
N4["FIP200"]
N0 -->|"activates"| N4
N5["ATG101"]
N0 -->|"activates"| N5
N6["ULK1"]
N0 -->|"activates"| N6
N7["Autophagy"]
N0 -->|"activates"| N7
N8["ATG14L"]
N8 -->|"activates"| N0
N9["ATG13"]
N9 -->|"activates"| N0
N10["ATG"]
N10 -->|"activates"| N0
N11["neurodegeneration"]
N0 -->|"implicated in"| N11
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classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 disease
class N2 gene
class N3 gene
class N4 gene
class N5 gene
class N6 gene
class N7 pathway
class N8 gene
class N9 gene
class N10 geneHypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ZDHHC13 in their description or question text
No additional research found