concept

USP11

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about USP11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

0Analyses

8Outgoing

7Incoming

0Experiments

0Debates

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💡 Concept Info

Name	USP11
Key Genes/Proteins	OTUD3, PGAM5, PTEN, STING, UBIQUITIN, USP13
Related Diseases	Neurotoxic Astrocyte Reactivity
Related Pathways	ubiquitin-proteasome

Wiki Pages (1)

Knowledge base pages for this entity

DUSP11 Gene

gene · 1300 words

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Pathway Diagram

graph TD
    USP11[USP11]
    USP11 -->|regulates| UBIQUITIN[UBIQUITIN]
    USP11 -->|promotes| Neurotoxic_Astrocyte_Reactivit[Neurotoxic Astrocyte Reactivity]
    USP11 -->|participates in| ubiquitin_proteasome[ubiquitin-proteasome]
    USP11 -->|regulates| USP13[USP13]
    USP11 -->|regulates| USP7[USP7]
    USP11 -->|expressed in| astrocytes[astrocytes]
    USP11 -->|data_in| benchmark_ot_ad_answer_key_USP[benchmark_ot_ad_answer_key:USP11]
    OTUD3[OTUD3] -->|regulates| USP11
    PTEN[PTEN] -->|regulates| USP11
    STING[STING] -->|inhibits| USP11
    PGAM5[PGAM5] -->|inhibits| USP11
    benchmark_ot_ad_answer_key_USP -->|data_in| USP11

Outgoing (8)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:USP11	data_in	dataset_row	0.00
PGAM5	associated_with	protein	0.95
UBIQUITIN	regulates	protein	0.90
Neurotoxic Astrocyte Reactivity	promotes	phenotype	0.90
ubiquitin-proteasome	participates_in	pathway	0.70
astrocytes	expressed_in	cell_type	0.60
USP13	regulates	gene	0.60
USP7	regulates	gene	0.60

Incoming (7)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:USP11	data_in	dataset_row	0.00
OTUD3	regulates	gene	0.60
PTEN	regulates	gene	0.60
STING	inhibits	gene	0.60
STING	regulates	gene	0.60
PGAM5	inhibits	gene	0.60
PGAM5	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning USP11 in their description or question text

No additional research found