protein

RBFOX1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RBFOX1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections

0Hypotheses

0Analyses

9Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for RBFOX1 Protein (A2BP1)

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🔬 Protein Info

Gene Symbol	RBFOX1
Full Name	RNA Binding Fox-1 Homolog 1 (RBFOX1)
Aliases	A2BP1
Chromosome	16p13.3 [@zha2023]
Protein Type	Gene
Function	Neuronal Splicing Programs: Controls inclusion/exclusion of alternative exons in hundreds of neuronal transcripts.
Subcellular Localization	pattern, localizing to the nucleus where it participates in splicing compartments, to the cytoplasm where it regulates R
Molecular Weight	47.6 kDa
Amino Acids	90 aa
UniProt ID	Q9NWB1
NCBI Gene ID	23027
Ensembl ID	ENSG00000078328
GeneCards	RBFOX1
Human Protein Atlas	RBFOX1
Associated Diseases	Als, Alzheimer, dementia, Ms, neurodegeneration
Interactions	ANO3
KG Connections	12 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RBFOX1 — AlphaFold Q9NWB1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

RNA Binding Fox-1 Homolog 1 (RBFOX1)

gene · 1224 words

→

RBFOX1 Protein (A2BP1)

protein · 1516 words

→

Pathway Diagram

graph TD
    RBFOX1["RBFOX1"]
    Als["Als"]
    Ms["Ms"]
    U2AF2["U2AF2"]
    neurodegeneration["neurodegeneration"]

    RBFOX1 -->|"associated with"| Als
    RBFOX1 -->|"associated with"| Ms
    RBFOX1 -->|"associated with"| U2AF2
    RBFOX1 -->|"implicated in"| neurodegeneration

    style RBFOX1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style Als fill:#3e1a1a,stroke:#ef5350,stroke-width:2px,color:#fff
    style Ms fill:#3e1a1a,stroke:#ef5350,stroke-width:2px,color:#fff
    style U2AF2 fill:#1a237e,stroke:#ce93d8,stroke-width:2px,color:#fff
    style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (9)

Target	Relation	Type	Str
Als	associated_with	disease	0.65
Ms	associated_with	disease	0.65
neurodegeneration	associated_with	disease	0.60
ALS	associated_with	disease	0.60
dementia	associated_with	disease	0.60
Alzheimer	associated_with	disease	0.60
neurons	expressed_in	cell_type	0.60
amyloid aggregation	interacts_with	process	0.60
U2AF2	associated_with	gene	0.60

Incoming (3)

Source	Relation	Type	Str
ANO3	interacts_with	gene	0.60
FOXA2	co_expressed_with	gene	0.50
PSMA3	co_expressed_with	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RBFOX1 in their description or question text

No additional research found