gene

RAB11B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAB11B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

31Connections
0Hypotheses
0Analyses
21Outgoing
10Incoming
0Experiments
0Debates

Summary

RAB11B is a gene implicated in neurodegeneration research. Key relationships include: associated with, regulates, implicated in. Associated with ALS, Als, Ms. Connected to 29 entities in the SciDEX knowledge graph.

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🧬 Gene Info
Gene SymbolRAB11B
Full NameRAB11B
AliasesPage for RAB11B
Chromosome19p13.2
FunctionRAB11B is a small GTPase that cycles between an active (GTP-bound) and inactive (GDP-bound) state.
Primary ExpressionBrain, Neurons, Neurosecretory cells
Molecular Weight24 kDa
Amino Acids218 aa
Pathwayspathway: **Receptor Recycling**
UniProt IDQ9UQ90
NCBI Gene ID5876
Ensembl IDENSG00000185236
GeneCardsRAB11B
Human Protein AtlasRAB11B
Associated DiseasesAls
InteractionsMAP1LC3B
KG Connections31 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: RAB11B — AlphaFold Q9UQ90 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

RAB11B - RAB11B

gene · 522 words

RAB11B Protein

protein · 935 words

Pathway Diagram

graph TD
    RAB11B["RAB11B"]
    Als{"Als"}
    RAB11B -->|"associated with"| Als
    Ms{"Ms"}
    RAB11B -->|"regulates"| Ms
    ALS{"ALS"}
    RAB11B -->|"associated with"| ALS
    RAB10["RAB10"]
    RAB11B -->|"associated with"| RAB10
    RAB3A["RAB3A"]
    RAB11B -->|"associated with"| RAB3A
    Exocytosis(["Exocytosis"])
    RAB11B -->|"associated with"| Exocytosis
    RAB3C["RAB3C"]
    RAB11B -->|"associated with"| RAB3C
    RAB5A["RAB5A"]
    RAB11B -->|"associated with"| RAB5A
    RAB5["RAB5"]
    RAB11B -->|"associated with"| RAB5
    RAB27B["RAB27B"]
    RAB11B -->|"associated with"| RAB27B
    RAB3B["RAB3B"]
    RAB11B -->|"associated with"| RAB3B
    RAB4B["RAB4B"]
    RAB11B -->|"associated with"| RAB4B
    RAB4B -->|"associated with"| RAB11B
    RAB27B -->|"associated with"| RAB11B
    RAB3C -->|"associated with"| RAB11B
    RAB5 -->|"associated with"| RAB11B
    RAB3B -->|"associated with"| RAB11B
    RAB5A -->|"associated with"| RAB11B
    RAB3A -->|"associated with"| RAB11B
    RAB10 -->|"associated with"| RAB11B
    ATP1A1["ATP1A1"]
    ATP1A1 -->|"regulates"| RAB11B
    MAP1LC3B["MAP1LC3B"]
    MAP1LC3B -->|"activates"| RAB11B
    style RAB11B fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (21)

TargetRelationTypeStr
Alsassociated_withdisease0.65
Alstransportsdisease0.65
Msregulatesdisease0.65
ALSassociated_withdisease0.65
APOPTOSISregulatesgene0.60

Incoming (10)

SourceRelationTypeStr
RAB4Bassociated_withgene0.60
RAB27Bassociated_withgene0.60
RAB3Cassociated_withgene0.60
RAB5associated_withgene0.60
RAB3Bassociated_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RAB11B in their description or question text

No additional research found