gene

RAB11A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAB11A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections

0Hypotheses

0Analyses

9Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for RAB11A - small GTPase regulating synaptic vesicle recycling, endosomal trafficking in neurodegenerative diseases

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🧬 Gene Info

Gene Symbol	RAB11A
Full Name	Ras-Related Protein Rab-11A
Aliases	Page for RAB11A
Function	RAB11A functions in the recycling endosome compartment
Molecular Weight	24 kDa
Amino Acids	216 aa
UniProt ID	RAB11A
Ensembl ID	ENSG00000103740
GeneCards	RAB11A
Human Protein Atlas	RAB11A
Receptor recycling	Controls recycling of AMPA, NMDA, and GABA receptors to the plasma membrane<sup>[1]</sup>
Synaptic plasticity	Essential for activity-dependent synaptic modification
Neurotrophin trafficking	Regulates BDNF/TrkB receptor recycling
Membrane protein turnover	Participates in cargo sorting in the recycling pathway
Cell division	Regulates cell polarity and cytokinesis (non-neuronal)
Associated Diseases	neurodegeneration
KG Connections	12 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: RAB11A — AlphaFold RAB11A Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    RAB11A["RAB11A"]
    Ms{"Ms"}
    RAB11A -->|"regulates"| Ms
    Als{"Als"}
    RAB11A -->|"regulates"| Als
    Amyotrophic_Lateral_Sclerosis{"Amyotrophic Lateral Sclerosis"}
    RAB11A -->|"regulates"| Amyotrophic_Lateral_Sclerosis
    DNAJC5(["DNAJC5"])
    RAB11A -->|"regulates"| DNAJC5
    ATG7(["ATG7"])
    RAB11A -->|"regulates"| ATG7
    VAMP7(["VAMP7"])
    RAB11A -->|"regulates"| VAMP7
    AMYOTROPHIC_LATERAL_SCLEROSIS(["AMYOTROPHIC LATERAL SCLEROSIS"])
    AMYOTROPHIC_LATERAL_SCLEROSIS -->|"regulates"| RAB11A
    RAB8A(["RAB8A"])
    RAB8A -->|"regulates"| RAB11A
    ALS(["ALS"])
    ALS -->|"regulates"| RAB11A
    style RAB11A fill:#1a3a4a,stroke:#ce93d8,stroke-width:3px,color:#ce93d8

Outgoing (9)

Target	Relation	Type	Str
Ms	regulates	disease	0.65
Als	regulates	disease	0.65
Amyotrophic Lateral Sclerosis	regulates	disease	0.65
AND	regulates	gene	0.60
DNAJC5	regulates	gene	0.60
ATG7	regulates	gene	0.60
VAMP7	regulates	gene	0.60
UBIQUITIN	regulates	gene	0.60
RAB27A	regulates	gene	0.60

Incoming (3)

Source	Relation	Type	Str
AMYOTROPHIC LATERAL SCLEROSIS	regulates	gene	0.60
ALS	regulates	gene	0.60
RAB8A	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RAB11A in their description or question text

No additional research found