gene 861 words KG: RAB11A
Contents

RAB11A — Ras-Related Protein Rab-11A

🧬 Gene Info
Gene SymbolRAB11A
Full NameRas-Related Protein Rab-11A
AliasesPage for RAB11A
FunctionRAB11A functions in the recycling endosome compartment
Molecular Weight24 kDa
Amino Acids216 aa
UniProt IDRAB11A
Ensembl IDENSG00000103740
GeneCardsRAB11A
Human Protein AtlasRAB11A
Receptor recyclingControls recycling of AMPA, NMDA, and GABA receptors to the plasma membrane<sup>[1]</sup>
Synaptic plasticityEssential for activity-dependent synaptic modification
Neurotrophin traffickingRegulates BDNF/TrkB receptor recycling
Membrane protein turnoverParticipates in cargo sorting in the recycling pathway
Cell divisionRegulates cell polarity and cytokinesis (non-neuronal)
Associated Diseasesneurodegeneration
KG Connections12 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

See Also (10)

Ubiquitin-Proteasome System Therapeutic Companies for P
company · KG edge: regulates
Amyotrophic Lateral Sclerosis
redirect · KG edge: regulates
Neurodegeneration
disease · KG edge: implicated_in
ATG7 Gene
gene · KG edge: regulates
DNAJC5 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

RAB8A regulates RAB11A
RAB11A regulates DNAJC5
RAB11A regulates ATG7
RAB11A regulates VAMP7
RAB11A regulates UBIQUITIN
RAB11A regulates RAB27A
AMYOTROPHIC LATERAL SCLEROSIS regulates RAB11A
ALS regulates RAB11A
RAB11A regulates Ms
RAB11A regulates Als

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