concept

PGS1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PGS1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

34Connections

0Hypotheses

0Analyses

24Outgoing

10Incoming

0Experiments

0Debates

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💡 Concept Info

Name	PGS1
Key Genes/Proteins	AND, App, BCS1L, CD14, FBXO7, GENES
Related Diseases	Als, ALS, Cardiomyopathy, Cardiovascular, Inflammation

Pathway Diagram

graph TD
    PGS1["PGS1"]
    PGS1 -.biomarker for.-> Septic_Cardiomyopathy["Septic Cardiomyopathy"]
    PGS1 -->|"target for"| Als["Als"]
    PGS1 -->|"target for"| B_Cell["B Cell"]
    PGS1 -->|"target for"| Rb["Rb"]
    PGS1 -->|"target for"| App["App"]
    CD14["CD14"] -->|"target for"| PGS1

Outgoing (24)

Target	Relation	Type	Str
Septic Cardiomyopathy	biomarker_for	disease	0.85
Als	therapeutic_target	disease	0.65
Cardiomyopathy	associated_with	disease	0.65
Als	associated_with	disease	0.65
Cardiovascular	associated_with	disease	0.65
ALS	associated_with	disease	0.65
Inflammation	associated_with	disease	0.65
MITOCHONDRIA	associated_with	gene	0.60
AND	associated_with	gene	0.60
HUB GENES	associated_with	gene	0.60
FBXO7	associated_with	gene	0.60
IMMUNE INFILTRATION	associated_with	gene	0.60
CD14	associated_with	gene	0.60
BCS1L	associated_with	gene	0.60
MRPS31	associated_with	gene	0.60
LYRM7	associated_with	gene	0.60
B Cell	associated_with	cell_type	0.60
TIMMDC1	associated_with	gene	0.60
INFLAMMATION	associated_with	gene	0.60
GENES	associated_with	gene	0.60
B Cell	therapeutic_target	cell_type	0.60
Rb	therapeutic_target	protein	0.60
App	therapeutic_target	protein	0.60
B Cell	expressed_in	cell_type	0.55

Incoming (10)

Source	Relation	Type	Str
CD14	therapeutic_target	gene	0.60
MRPS31	associated_with	gene	0.60
TIMMDC1	associated_with	gene	0.60
FBXO7	associated_with	gene	0.60
BCS1L	associated_with	gene	0.60
IMMUNE INFILTRATION	associated_with	gene	0.60
MITOCHONDRIA	associated_with	gene	0.60
GENES	associated_with	gene	0.60
INFLAMMATION	associated_with	gene	0.60
LYRM7	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PGS1 in their description or question text

No additional research found