gene

NGN1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NGN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

12Outgoing

4Incoming

0Experiments

0Debates

No summary available yet.

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🧬 Gene Info

Gene Symbol	NGN1
Full Name	Neurogenin-1
Chromosome	9q21.13.
Protein Type	Transcription Factor
Function	Neural plate border specification by BMP and Wnt signaling
Molecular Weight	30 kDa
Amino Acids	282 aa
Exons	3
Pathways	Wnt signaling
UniProt ID	Q9Y4Z4
NCBI Gene ID	4745
Ensembl ID	ENSG00000166845
OMIM	604663
GeneCards	NGN1
Human Protein Atlas	NGN1
Associated Diseases	neurodegeneration
Interactions	GENES, NGN2
KG Connections	16 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: NGN1 — AlphaFold Q9Y4Z4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ngn1

gene · 2073 words

→

Pathway Diagram

flowchart TD
    N0["NGN1"]
    N1["NGN2"]
    N0 -->|"regulates"| N1
    N2["MEF2C"]
    N0 -->|"regulates"| N2
    N3["EPHA5"]
    N0 -->|"regulates"| N3
    N4["NLGN1"]
    N0 -->|"regulates"| N4
    N5["DCC"]
    N0 -->|"regulates"| N5
    N6["Neuron"]
    N0 -->|"regulates"| N6
    N7["AND"]
    N0 -->|"regulates"| N7
    N8["App"]
    N0 -->|"regulates"| N8
    N9["GENES"]
    N9 -->|"activates"| N0
    N1 -->|"regulates"| N0
    N2 -->|"regulates"| N0
    N10["Cortex"]
    N0 -->|"expressed in"| N10
    N0 -->|"expressed in"| N6
    N11["Genes"]
    N0 -->|"regulates"| N11

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 gene
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 gene
    class N7 gene
    class N8 protein
    class N9 gene

Outgoing (12)

Target	Relation	Type	Str
Neuron	regulates	cell_type	0.60
AND	regulates	gene	0.60
App	regulates	protein	0.60
NGN2	regulates	gene	0.60
MEF2C	regulates	gene	0.60
EPHA5	regulates	gene	0.60
NLGN1	regulates	gene	0.60
DCC	regulates	gene	0.60
Cortex	expressed_in	brain_region	0.55
Neuron	expressed_in	cell_type	0.55
NGN2	activates	gene	0.50
Cortex	regulates	brain_region	0.50

Incoming (4)

Source	Relation	Type	Str
GENES	activates	gene	0.60
MEF2C	regulates	gene	0.60
NGN2	regulates	gene	0.60
EPHA5	regulates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NGN1 in their description or question text

No additional research found